Crystallization ceruloplasmin

Ceruloplasmin from other sources. Alternative approaches could involve the isolation of ceruloplasmin from other sources yielding crystals with a tighter molecular packing and higher resolution diffraction patterns. 

Loss of copper. Solutions and crystals of ceruloplasmin that have been allowed to stand for several weeks partially lose their blue color and this may indicate changes in copper oxidation state and/or loss of copper. A series of experiments are required to determine whether any copper loss is site preferential and how this is affected by anionic inhibitors. 

Figure 10 Schematic view of the crystal structure of human ceruloplasmin (after Zaitseva et u/. Lindley...

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