Metastases cerebral

OLIVA, J., et al., Detection of an unknown cerebral metastasis using radio-immunoscintigraphy with the monoclonal antibody ior-EGF-R3-Tc-99rn, Rev. Esp. Med. Nucl. 16 (1997) 321-323. 

Fortin D, Gendron C, Boudrias M, Garant MP. Enhanced chemotherapy delivery by intraarterial infusion and blood-brain barrier disruption in the treatment of cerebral metastasis. Cancer 2007 109 751-760. 

Brain metastasis is the most common neurologic complication seen in patients with cancer. Approximately 170,000 patients develop brain metastases in the United States each year.20 Many malignancies are frequently associated with brain metastases (Table 96-7). While melanoma is the tumor type most likely to metastasize to the brain, brain metastases owing to lung and breast cancers are seen more often because they are among the most common cancers. In addition, brain metastasis may be diagnosed at the same time as the primary malignancy in around 20% of cases.22 Around 80% of brain metastases occur in the cerebral hemispheres, 15% in the cerebellum, and 5% in the brain stem. 

Fig. 8.2. Examples of tumors that may cause symptoms mimickirtg TIA (a) mertirtgloma (b) hemorrhagic melanoma metastasis and (c) multiple cerebral metastases in a patient with lung adenocarcinoma.

---