Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

CEPH pedigrees

The observed CEPH population mean IC50 for both docetaxel and 5-fluorouracil was similar to IC50 values observed across the NCI60 panel of human tumor cell lines (http //dtp.nci.nih.gov) (17). In addition, docetaxel- and 5-fluorouracil-induced cell death is mediated by caspase-3 cleavage, similar to that observed in tumor cells (17). These data are encouraging for the use of CEPH pedigrees as a discovery tool. However, the ultimate proof of the value of the cell-based models will be the human validation of markers derived from this process. These studies he ahead and will help position cell-based models in their correct place in the drug development process. [Pg.29]

Schork NJ, Gardner JP, Zhang L et al. Genomic association/linkage of sodium lithium countertransport in CEPH pedigrees. Hypertension 2002 40 619-628. [Pg.30]

See other pages where CEPH pedigrees is mentioned: [Pg.20]    [Pg.23]    [Pg.26]    [Pg.27]    [Pg.393]    [Pg.397]    [Pg.116]    [Pg.130]    [Pg.130]    [Pg.130]    [Pg.20]    [Pg.23]    [Pg.26]    [Pg.27]    [Pg.393]    [Pg.397]    [Pg.116]    [Pg.130]    [Pg.130]    [Pg.130]    [Pg.26]    [Pg.27]    [Pg.255]   
See also in sourсe #XX -- [ Pg.130 ]



SEARCH



Pedigree

© 2024 chempedia.info