Operating safety centrifuges

Examples of some devices which meet only the first criterion are the safety blender (Figure 10.1), centrifuge safety tubes (Figure 10.2), and flexible film containers (Figure 10.3). These devices do limit the amount of material used and contained, but they do not allow easy transfer or decontamination. Therefore, they are not true primary barriers however, they do provide the best possible containment available for mixing and centrifuging operations. The most familiar primary barrier device that meets all three criteria is the biolog-... 

A good discussion of centrifuge safety design features and operating practices is found in an IChemE publication (1987). 

Rupture disk, 455 Safety relief valves, 454, 467, 481 Specifications, centrifugal pumps, 209 Spray nozzle particle size, 225 Standards and Codes, 31, 32, 33 Static electricity, 536 Static mixing, 332 Applications, 336 Calculations, 337, 338 Materials of construction, 337 Principles of operation, 335 Type of equipment 334-338... 

System total heads should be estimated as accurately as possible. Safety factors should never be added to these estimated total head values. This is illustrated by Figure 4.8. Suppose that OAi is the correct curve and that the centrifugal pump is required to operate at point A. Let a safety factor be added to the total head values to give a system curve OA2. On the basis of curve OA2, the manufacturer will supply a pump to operate at point A2. However, since the true system curve is OA, the pump will operate at point Ai. Not only is the capacity higher than that specified, but the pump motor may be overloaded. 

Fuzes contain safety devices that tend to prevent functioning until after the fuze has been subjected to centrifugal and setback forces, after the round is fired. In the so-called bore-safe fuzes, the path of the explosive train is interrupted so that, while the projectile is still in the bore of the weapon, premature expln is prevented should any of the more sensitive fuze elements (such as primer and/or detonator) start to function. Interruption is usually achieved by inserting out-of-line components or interrupter blocks or slides. Although this leaves the fuze in an unarmed position, it would not be considered safe in handling or shipping, unless the fuze was not provided with safety devices such as safety wires or cotter pins. These outside devices must be removed prior to inserting the fuzed round of ammunition into gun barrel, but the fuze will still be unarmed because some of its inside parts are not free to move to their proper positions so that the fuze may operate in its intended manner... 

Continuous product flows under high-pressure conditions (p > 30 MPa) can only be achieved with hermetic centrifugal pumps. Although the two drive systems that can be used - the permanent magnet coupling and the asynchronous canned motor - have the same mode of operation, they differ in their applications and their safety ranges. 

The versatile drive system of the asynchronous canned motor has set fresh yardsticks for centrifugal pumps operating under high-pressure conditions. The operating limits for pressure, temperature and toxicity of the flow product have been extended by some orders of magnitude. This is the logical result of the response to heightened safety environment requirements, and means that technical processes can now be implemented for the manufacture of new products. 

To reliably perform qualitative and quantitative analyses on body fluids and tissue, the clinical laboratorian must understand the basic principles and procedures that affect the analytical process and operation of the clinical laboratory. These include the knowledge of (1) the concept of solute and solvent, (2) units of measurement, (3) chemicals and reference materials, (4) basic techniques, such as volumetric sampling and dispensing, centrifugation, measurement of radioactivity, gravimetry, thermometry, buffer solution, and processing of solutions, and (5) safety. ... 

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