Cellulose-chitin hybrid enzymatic polymerization

Scheme 8 Enzymatic polymerizations to a cellulose-chitin hybrid polysaccharide.

Kobayashi et have also investigated other modes of enzymatic polymerization to produce a novel cellulose-chitin hybrid polysaccharide. A sugar fluoride monomer of GlcNAc/3(l 4)Glc (17) was designed as a TSAS monomer for polymerization catalyzed by cellulase from Trichoderma viride. In the polymerization, monomer 17 was recognized by cellulase from T. viride, leading to a cellulose-chitin hybrid polysaccharide 18 with perfect regioselectivity and stereochemistry (Scheme 17). 

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