Cellular structures, inorganic system

Our treatment of basic principles of water-solute relationships involves a bottom-up approach that begins with a basic physical-chemical analysis of how fundamental water solute interactions have set many of the boundary conditions for the evolution of life. We discuss how the properties of macromolecules and micromolecules alike reflect selection based on such fundamental criteria as the differential solubilities of different organic and inorganic solutes in water, and the effects that these solutes in turn have on water structure these are two closely related issues of vast importance in cellular evolution. With these basic features of water-solute interactions established, we will then be in a position to appreciate more fully why regulation of cellular volume and the composition of the internal milieu demands such precision. We then can move upwards on the reductionist ladder to consider the physiological mechanisms that have evolved to enable cells to defend the appropriate solutions conditions that are fit for the functions of macromolecular systems. This multitiered analysis is intended to help provide answers to three primary questions about the evolution and regulation of the internal milieu ... 

By now we know a large number of oscillatory reactions, not only in chemistry - as exemplified by the famous Belousov-Zhabotinsky reaction - but also in biochemical and cellular systems. It is interesting to observe that in oscillations in inorganic chemistry the molecules are simple but the mechanisms are highly complex, whereas in biochemistry the molecules responsible for rhythmic phenomena possess a complex structure (enzymes or receptors. ..) whereas the mechanisms often are simple. 

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