Cell culture estrogen bioassays

The chlorinated pesticides DDT and chlordecone are known to generate deleterious reproductive effects. In a bioassay of these and other chlorinated pesticides on cultured human breast estrogen-sensitive MCF7 cells, it was shown that dieldrin, toxaphene, and endosulfan have estrogenic properties comparable to those of DDT and chlordecone. When tested together, the mixture of the three pesticides induced estrogenic responses... 

In an in culture bioassay using human-breast estrogen-sensitive MFC7 cells to assess the estrogenicity of several pesticides, it was found that mixtures of the pesticides induced estrogenic responses at lower concentrations than those required for the single pesticides. The pesticides tested included DDT, chlordecone, dieldrin, toxaphene, and endosulfan [94],... 

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