Ceftazidime dosage

To conduct retrospective DUE to determine potential cost savings of ceftazidime dosage adjustment OD None None DCA Ceftazidime dosing in elderly found to be in excess of labeled dosing because renal function not considered Input costs not considered clinical outcomes not considered... 

Empirical regimens containing Cefepime, ceftazidime, imipenem, meropenem Vancomycin dosages may be adjusted based on... 

Renal function Impairment- Ceftazidime is excreted by the kidneys, almost exclusively by glomerular filtration. In patients with impaired renal function (glomerular filtration rate (GFR) less than 50 mL/min), reduce dosage to compensate for slower excretion. In patients with suspected renal insufficiency, give an initial loading dose of 1 g. Estimate GFR to determine the appropriate maintenance dose. 

Ceftazidime (Fortaz, Tazicef, Tazidime) is a cephalosporin antibiotic that is used for infections of, for example, the lower respiratory tract, skin and urinary tract. It is excreted, almost exclusively, by glomerular filtration. Table 4.4 shows the relationship between the creatinine clearance and recommended dose or dosage regimen. 

The clearance of ceftazidime is significantly reduced by Indometacin in neonates, and dosage adjustments are likely to be necessary. 

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