Tobramycin Cefamandole

Other antimicrobial agents that have been incorporated into PMMA beads and shown to have useful elution profiles include penicillin G (ben-zylpenicillin), ampicillin, amoxicillin, flucloxacillin, amoxiciUin-clavulanate, cefamandole, cefazolin, tobramycin, netilmicin, imipenem, erythromycin, ciprofloxacin, trimethoprim-sulfamethoxazole, chloramphenicol and vancomycin (Ethell et al 2000, Mader et al 1997, Veyries et al 2000). 

Extracted cefamandole, cefazolin, cefoxitin, cephapirin, chloramphenicol Simultaneous acetaminophen, N-acetylprocainamide, cefaclor, cephalexin, cephalothin, ci-metidine, miconazole, moxalactam, procainamide, sulfamethoxazole, theophylline, tobramycin, vancomycin... 

Noninterfering acetaminophen, N-acetylprocainamide, amikacin, amitriptyline, ampicil-lin, carbamazepine, cefamandole, cefazolin, cefoperazone, cefotaxime, cefoxitin, ceftazidime, ceftizoxime, cephalexin, cephalothin, cephapirin, chloramphenicol, ciprofloxacin, clonazepam, (yclosporine, desipramine, digoxin, disopyramide, ethosuximide, gentamicin, haloperidol, imipramine, kanamycin, lidocaine, mezlocillin, netilmicin, nortriptyline, phenobarbital, phenytoin, primidone, procainamide, propranolol, quinidine, salicylic acid, streptomycin, sulfamethoxazole, theophylline, thiamphenicol, ticarcillin, tobramycin, trimethoprim, vancomycin... 

Another study assessing the risk factors for nephrotoxicity with aminoglycosides (tobramycin and gentamicin) enrolled 1489 patients, 157 of whom developed clinical nephrotoxicity. Of these patients 118 had no immediately identifiable cause (such as acute renal failure) and further evaluation of other risk factors found that the concurrent use of cephalosporins (including cefazolin, cefotaxime, cefoxitin, cefamandole, ce-furoxime, ceftriaxone, and ceftazidime) significantly increased the risk of nephrotoxicity. ... 

The interaction between a number of antibiotics (oxytetracycline, tetracycline, tobramycin, clindamycin, cefamandole, bacitracin and chloramphenicol) and surgical metallic materials (316L stainless steel, Co-Cr and commercially pure Ti) has shown that only oxytetracycline exerts an effect on the electrochemical response. For all the materials this antibiotic shifted the corrosion potential of abraded surfaces in the noble direction, as seen in Figure 9.8. 

Due to the increasing resistance of most staphylococci to gentamicin, other alternative antibiotics such as vancomycin, tobramycin, chndamycin, fusidic acid, cefamandol. 

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