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CCR5 Pfizer

INCB3284 Incyte Pharmaceuticals/ Pfizer Phase Ha RA, obese insulin-resistant. It also presents mild anti-CCR5 effect. 111, 112, 124... [Pg.159]

Fig. 4. Structure of UK-427,857 (maraviroc), a CCR5-specific antagonist from Pfizer currently in phase III studies for HIV treatment. The original hit from the high-throughput screening, compound UK107,543, is also shown. Fig. 4. Structure of UK-427,857 (maraviroc), a CCR5-specific antagonist from Pfizer currently in phase III studies for HIV treatment. The original hit from the high-throughput screening, compound UK107,543, is also shown.
Maraviroc, UK-427857, CCR5 agonist MLN1202, Pfizer Blocks HIV-1 infection HIV... [Pg.149]

The Pfizer group has also disclosed the structure of a range of distinct CCR5 antagonists 12 related to the Schering compounds depicted below. A combination of... [Pg.217]

See other pages where CCR5 Pfizer is mentioned: [Pg.354]    [Pg.354]    [Pg.354]    [Pg.354]    [Pg.354]    [Pg.187]    [Pg.192]    [Pg.43]    [Pg.380]    [Pg.185]    [Pg.354]    [Pg.214]    [Pg.215]    [Pg.216]    [Pg.217]    [Pg.349]   
See also in sourсe #XX -- [ Pg.215 , Pg.216 , Pg.217 ]



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CCR5

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