Cationic Polymers for Drug Delivery across the BBB

Cationic bovine serum albumin (CBSA) conjugated with poly(ethylene glycol)-poly(lactide) (PEG-PLA) nanoparticles was developed and its effects were evaluated as a potential drug delivery device across the BBB. The [Pg.548]

Several peptides have been studied with antimicrobial and antifungal properties for BBB delivery to avoid infections. Cholesterol-conjugated G3R6TAT (CG3R6TAT) cationic nanoparticles exhibited strong antimicrobial activities against various types of microbes in vitro. This peptide contains the TAT sequence. The prepared nanoparticles were investigated for treatment [Pg.551]

Begley, M. Brightman, in Peptide Transport and Delivery into the Central Nervous System, ed. L. Prokai, aand K. Prokai-Tatrai Birkhauser Basel 2003, vol. 61, pp. 39-78. [Pg.554]

Kraeger, W. Hartig, A. Reiehenbaeh, I. Beehmann and D. Michalski, PLoS One, 2013, 8, e56419. [Pg.554]

Deracinois, S. Duban-Deweer, G. Pottiez, R. Cecchelli, Y. Karamanos and C. Flahaut, PLoS One, 2012, 7, e48428. [Pg.554]

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