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Cassia leptophylla

Alexandre-Moreira, M. S Viegas Jr., C., Palhares de Miranda, A. L. and Bolzani, V. S. 2003. Antinociceptive profile of (—)-spectaline A piperedine alkaloid from Cassia leptophylla. Planta Medica, 69 795-799. [Pg.260]

In an effort to uncover anticancer active metabolites in Brazilian plants, in early 1993 we initiated active collaboration with several Brazilian natural products chemists. Out of the large number of extracts brought to our laboratory by Dr. Vanderlan da S. Bolzani and screened in our mechanism-based yeast bioassay, extracts derived from two leguminous plants were selected for further studies. Based on preliminary investigation the bioactive methanolic chloroform extract of the leaves of Cassia leptophylla which was shown to contain bioactive alkaloidal constituents was further processed for alkaloids. The alkaloid fraction thus obtained was fractionated by column chromatography on alumina, followed by Silica gel preparative TLC and reversed-phase TLC to afford seven piperidine alkaloids [55] (-)-spectaline (68), (-)-spectalinine (69), canavaline (70), leptophyllin A (71), 3-acetylleptophyllin A (72), iso-... [Pg.486]

Bioactivity data for piperidine alkaloids from Cassia leptophylla. ... [Pg.487]

Bolzani VS, Gunatilaka AAL, Kingston DGI. Bioactive and other piperidine alkaloids from Cassia leptophylla. Tetrahedron 1995 51 5929-34. [Pg.241]

Alkaloid from leaves of Cassia leptophylla (Leguminosae). [Pg.262]

See other pages where Cassia leptophylla is mentioned: [Pg.151]    [Pg.259]    [Pg.572]    [Pg.468]    [Pg.486]    [Pg.486]    [Pg.262]    [Pg.567]    [Pg.151]    [Pg.259]    [Pg.572]    [Pg.468]    [Pg.486]    [Pg.486]    [Pg.262]    [Pg.567]   
See also in sourсe #XX -- [ Pg.151 ]

See also in sourсe #XX -- [ Pg.20 , Pg.486 , Pg.487 ]

See also in sourсe #XX -- [ Pg.20 , Pg.486 , Pg.487 ]

See also in sourсe #XX -- [ Pg.206 ]



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