Cartilage, growing, damage

Which of the following may cause damage to growing cartilage ... 

The answer is a. (Katzung, p 800.) Fluoroquinolones are not recommended in patients less than 18 years old. They have a tendency to damage growing cartilage and cause arthropathy The arthropathy is generally reversible. Tendinitis may occur, and in rare instances in adults, this finding may lead to tendon ruptures. 

Fluoroquinolones may damage growing cartilage and cause an arthropathy. Thus, these drugs are not routinely recommended for patients under 18 years of age. However, the arthropathy is reversible, and there is a growing consensus that fluoroquinolones may be used in children in some cases (eg, for treatment of pseudomonal infections in patients with cystic fibrosis). Tendinitis, a rare complication that has been reported in adults, is potentially more serious because of the risk of tendon rupture. Risk factors for tendonitis include advanced age, renal insufficiency, and concurrent... 

Growing cartilage the vasculature growing bones Medium Destruction of proliferating chondroblasts or osteoblasts damage to the endothelium destruction of connective tissue cells chondroblasts or osteoblasts... 

Quinolones May damage growing cartilage may cause blood glucose alterations hemolysis in patients with G5PD deficiency exacerbation of myasthenia gravis acute renal failure. 

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