Carp extract

FU or 5-FU plus carp extract were administered orally twice... 

Carp extract was administered orally twice daily until death, daily for g days. On day 9, blood and tissues were obtained, starting 12 h after implantation of tumor cells. Results are expressed as means S.E. of 10 nuee. 

Fig. 11. Inhibitory effect of carp extract on myelotoxicity (reduction of leukocyte number) induced by 5-FU.

Kimura, Y. Okuda, H. Prevention by carp extract of myelotoxicity... 

Carp (Cyprinus carpi ) has been used in Korea, China and Japan as a health food source. In ancient Chinese medicine, carp was eaten as diuretic, and as a remedy for eye fatigue. In Japan, carp meat and blood have traditionally been eaten as a tonic. Although it has recently been thought that carp extract has antitumor activity, the basis for this hearsay is unclear. Therefore, to clarify whether carp extract has antitumor effects, the antitumor effect of carp extract, and the combined effect of 5-FU plus carp extract on antitumor activity and side effects were investigated in sarcoma 180-bearing mice. 

Effects of carp extract on sinvival time in ascites-type sarcoma 180-bearing mice. 

Carp extract was orally administered twice daily until death, starting 12 h after implantation of tumor cells. 

Fio. 21. Ultracentrifugal pattern of a 10-minute actomyosin of the carp extracted at M 0.53 and neutral pH (after hamoib, 1955). 

Fig. (59). Antitumor effects of 5-Fu and 5-FU plus carp extract 5-FU or 5-FU plus carp extract were administered orally twice daily for 8 days. On day 9, blood and each tissues were obtained.

---