Cardiac Ionic Currents of Particular Interest

This paradigm also offers the facihtation of more informative package inserts at the time of a new drug s marketing approval and also the relabeling of those compounds that currently have QTc warnings and precautions but for which a true low proarrhythmic risk can now be identified. 

Numerous overlapping ionic currents contribute to the determination of the morphology and duration of the ventricular action potential those discussed in this chapter are summarized in Table 9.1. 

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