Carbonic anhydrases classification

Diuretics John P Howe Introduction Classification Osmotic diuretics Carbonic anhydrase inhibitors Loop diuretics inhibitors of Na+/K+/2CI- transport Thiazide diuretics... 

B. Aquation/Decarboxylation Reaction Discovery and Classification of Carbonic Anhydrases... 

The aqueous suppressants include the P-adrenergic antagonists, a-agonists, carbonic anhydrase inhibitors (CAIs topical and oral), and hyperosmotics (intravenous). The topical fiarms of this classification are used routinely in clinical practice. The oral and intravenous formulations are generally reserved fiar use under special circumstances. 

Reflecting the lack of in-depth experimental data available at this time, even the classiflcation of metal-dependent enzymes was notably nonsystematic. In an early review, five categories were set forth heme, copper-containing, proteolytic, carbonic anhydrase, and phosphatase . A later classification" was made according to the types of reactions catalyzed electron transfer or redox (Cu, Fe, Mo), group transfer (Mg, Mn), decarboxylations and hydrolyses (Mn, Zn), and binding of pyridine nucleotide cofactors (Zn). 

Classification of inhibitors of bovine carbonic anhydrase II according to the electronic spectral properties of the adducts with cobalt(ll) derivatives. ... 

Carbonic anhydrases, also known as carbonate dehydratase and placed in enzyme classification 4.2.1.1, are zinc metalloproteins that catalyze the reversible hydration of carbon dioxide to bicarbonate (Eq. 1) ... 

Carbohydrates, Recognition of, p. 169 Carbonic Anhydrase Models, p. 178 Carcerands and Hernicarcerands. p. 189 Cation-n Interactions, p. 214 Cavitands, p. 219 Chiral Guest Recognition, p. 236 Classical Descriptions of Inclusion Compounds, p. 253 Classification and Nomenclature of Supramolecular Compounds, p. 261 Clathrate Hydrates, p. 274 Conzplexation of Fullerenes, p. 302 Concepts in Ciystal Engineering, p. 319 Crown Ethers, p. 326 Cryptands, p. 334 Cryptophanes, p. 340 Cyclodextrins, p. 398... 

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