Carbon monoxide organopalladium intermediates

Organopalladium intermediates are also involved in the synthesis of ketones and other carbonyl compounds. These reactions involve acylpalladium intermediates, which can be made from acyl halides or by reaction of an organopalladium species with carbon monoxide. A second organic group, usually arising from any organometallic reagent, can then form a ketone. Alternatively, the acylpalladium intermediate may react with nucleophilic solvents such as alcohols to form esters. [Pg.708]

Organopalladium(n) intermediates generated from halides or triflates by oxidative addition react with carbon monoxide in the presence of alcohols to give carboxylic acids246 or esters.247... [Pg.751]

This reaction proceeds via transmetallation to generate an organopalladium intermediate which readily adds across the carbon-carbon double bond of the alkene. Rapid cis-palladium hydride / elimination generates the substituted alkene. Analogous reactions - with carbon monoxide are used to synthesize carbonyl compounds ... [Pg.215]

If the coupling reaction is carried out in the presence of carbon monoxide, insertion of CO into the intermediate organopalladium(II) species 199 occurs. This generates an acyl palladium(II) species that undergoes transmetallation with the organometallic species, leading to a ketone product (1.202). [Pg.91]

The reactions with carbon monoxide involve addition of the organopalladium intermediate to carbon monoxide ... [Pg.274]