Carbon detection of proton magnetisation

A recent example from the literature which is particularly illustrative of this approach is the so-called WISE experiment [137], in which the lineshape is detected as a function of chemical shift in a two-dimensional experiment. This sequence has also been modified to permit observation of the effects of spin diffusion in what is essentially a heteronuclear two-dimensional variant of the Goldman-Shen type experiment. This has allowed clear observation of the effects of micro heterogeneity in compatible blends of PS/PVME. 

The use of detection obviously adds to these experiments by allowing separate analysis for the different chemically resolved peaks in the spectrum, but it is important to note that this does not imply that what is detected is the intrinsic behaviour of the protons directly bonded to the carbons being 

A useful analysis of the utility of such experiments in heterogeneous polymer systems has been made by Tekely et al. [100], and several other authors have made extensive use of such measurements (see, for example [138]). While the gain in chemical selectivity is somewhat balanced by the accompanying loss in sensitivity, there are occasions when detection of the magnetisation via the chemical shift allows analyses which would otherwise be difficult or impossible [102]. 

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