Carbohydrazide IV-carboxamide

Many of the iV-alkyl and iV-aryl derivatives of urazine have been synthesized and characterized, but the parent substance is not well known. In the past, urazine has been prepared by thermal deammonation of carbohydrazide-iV-carboxamide [eq. (I)],1 fusion of hydrazidicarbamide with hydrazinium hydrogen sulfate [eq. (2)],2 fusion of earbohy-drazide with urea [eq. (3)],3 action of sodium hypobromite on semicarbazide [eq. (4)],4 reaction of dichlorourea with concentrated ammonia [eq. (5)],5 and the reaction between 1,2 hydrazine carboxylic ester and hydrazine hydrate... 

Many hydrazine derivatives condense readily with potassium cyanate to give AT-substituted semicarbazides. Car-bohydrazide reacts with 1 or 2 mols of potassium cyanate to form carbohydrazide-iV-carboxamide or carbohydrazide-iVjiV -dicarboxamide. 

Carbohydrazide-iV-carboxamide is a white, nonhygro-scopic, crystalline substance which is insoluble in water and in alcohol and other organic solvents. It is soluble in mineral-acid solutions, from which it may be reprecipitated by the addition of ammonia however, it dissolves in sodium hydroxide with decomposition. 

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