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Carbohydrate Scaffolds in Combinatorial Chemistry

The complex and polyfunctional nature of carbohydrates has made the development of automated methods for oligosaccharide libraries extremely slow. However, carbohydrates can serve as excellent library scalfolds [27]. Several chiral hydroxyl groups, upon appropriate modifications and utilization, could be utilized further in the display of chemical diversities. This approach could provide a novel entry to different classes of compounds to be explored for drug-like properties. [Pg.739]

SCHEME 14.11 Carbohydrate-based small molecule scaffolds. [Pg.739]

SCHEME 14.13 Solid-phase synthesis of levoglucosan derivatives. [Pg.740]

6 CARBOHYDRATE/GLYCOCONJUGATE-UKE COMPOUNDS (GLYCOMIMETICS) BY COMBINATORIAL CHEMISTRY [Pg.741]

See other pages where Carbohydrate Scaffolds in Combinatorial Chemistry is mentioned: [Pg.739]    [Pg.749]    [Pg.729]    [Pg.739]    [Pg.739]    [Pg.749]    [Pg.729]    [Pg.739]    [Pg.218]    [Pg.813]    [Pg.804]    [Pg.997]    [Pg.1235]    [Pg.181]    [Pg.20]    [Pg.574]    [Pg.1206]    [Pg.2438]    [Pg.415]    [Pg.412]    [Pg.178]    [Pg.249]    [Pg.412]    [Pg.1104]    [Pg.1112]   


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