Carbenes structure and reactivity

The relationship between A -heterocydic carbene structure and reactivity... 

In each case, our well-developed understanding of the relation between carbenic structure and reactivity permits us to harness the innate reactivity of very diverse divalent carbon species, converting them Ifom reactive intermediates to useful reagents. The subtle control of carbenic reactivity demonstrated in the following pages is a tribute to years of incisive experimentation by many scientists. The four founders would be very pleased. 

Isotopic labeling experiments. Fisher carbenes structure and reactivity. 

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