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Capsaicin antinociceptive action

In recent decade, TTX-R sodium channels were further focused because they are related to C fibers, which transmit pain sensation to the brain. If a chemical acts on TTX-R sodium channels but does not act on TTX-S sodium channels, this chemical is supposed to be a useful antinociceptive. The fact indicated that capsaicin blocked unmyelinated C fibers of human sural nerve in vitro and there was a good correlation between the sensitivity of C fibers to capsaicin and their resistance to TTX. The C fiber action potentials were found to be completely blocked by capsaicin in the presence of TTX (Grosskreutz et al., 1996). [Pg.204]

See other pages where Capsaicin antinociceptive action is mentioned: [Pg.312]    [Pg.445]    [Pg.191]    [Pg.205]    [Pg.106]    [Pg.245]    [Pg.438]    [Pg.446]    [Pg.468]    [Pg.502]    [Pg.514]    [Pg.159]    [Pg.160]    [Pg.323]    [Pg.92]    [Pg.210]    [Pg.509]    [Pg.100]   
See also in sourсe #XX -- [ Pg.30 , Pg.206 ]

See also in sourсe #XX -- [ Pg.206 ]



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