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Cancer development, initiation-promotion

As the involvement of free radicals in both the initiation and promotion stages of cancer has been demonstrated (see above), it is reasonable to suggest that antioxidants may be applied for cancer treatment and prevention. Therefore, already for a long time, the effects of many antioxidants and antioxidant enzymes on cancer development have been studied under in vitro and in vivo conditions. Naturally from the beginning, much attention has been drawn to the study of possible SOD effects. Unfortunately, natural SOD has a short circulation lifetime and unable to penetrate into cells. Therefore, various SOD mimics were studied as potential anticancer drugs. [Pg.929]

See other pages where Cancer development, initiation-promotion is mentioned: [Pg.310]    [Pg.1278]    [Pg.458]    [Pg.926]    [Pg.303]    [Pg.6]    [Pg.927]    [Pg.219]    [Pg.33]    [Pg.43]    [Pg.32]    [Pg.120]    [Pg.746]    [Pg.83]    [Pg.538]    [Pg.30]    [Pg.134]    [Pg.310]    [Pg.135]    [Pg.97]    [Pg.310]    [Pg.2659]    [Pg.69]    [Pg.455]    [Pg.459]    [Pg.55]    [Pg.309]    [Pg.252]    [Pg.256]    [Pg.257]    [Pg.274]    [Pg.746]    [Pg.131]    [Pg.123]    [Pg.148]    [Pg.183]    [Pg.184]    [Pg.420]    [Pg.485]    [Pg.663]    [Pg.27]    [Pg.1776]    [Pg.169]    [Pg.236]    [Pg.238]    [Pg.323]    [Pg.324]    [Pg.213]    [Pg.382]   


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Initiation development

Initiation-promotion

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