Can a Reaction Be Catalyzed in Both Directions

This is a question that requires a heavy use of the energy span model including concentrations (Eqs. (9.15)-(9.17)), but it is possible to find earlier derivations 

10) The only experiment-theory discrepancy in these studies is in the overestimation of the theoretical energy span (the exercise of calculating both the experimental and the theoretical 5 is left to the readers). 

IS Myth A catalyst can catalyze a reaction in both directions. 

0 Fact The catalyst may be efficient in one direction, and a failure in the other. 

This myth is originated from the indisputable fact that a catalyst does not change the global equilibrium constant [6, 7, 29]. Indeed, accelerating the reaction exclusively in one direction would imply the violation of the principle of microscopic reversibiUty, opening the door to the creation of a perpetuum mobile [ 10,11, 24]. 

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