Caltha leptosepala

N.A. Caltha leptosepala DC No information is available in the Uterature. Diaphoretic, emetic, expectorant. Diuretic, laxative, antitumor activity.347... 

It has been shown that (+)-magnoflorine (47) and (+)-JViV-dimethyl-lindcarpine (48) are easily distinguishable by analysis of their H n.m.r. spectra in different solvents. On this basis, the quaternary aporphine found in Caltha leptosepala is clearly (+)-magnoflorine.52... 

Senecionine (37) has been isolated by Stermitz and Adamovics from the roots and aerial parts of Caltha leptosepala DC. and C. biflora DC. in very low yield (0.001—0.005% of dry weight), together with known aporphine alkaloids. This is the first report of pyrrolizidine alkaloids in the Ranunculaceae, and the first recorded co-occurrence of pyrrolizidine and aporphine alkaloids. 

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