Calcium parallel plate

Fig. 9. Crystal structure of group IV cytosolic PLAj showing the C2 and catalytic domain. The two calcium ions bound to the C2 domain and the active-site Ser-228 are highlighted. The phospholipid interface would be parallel to the top surface of the molecule as shown. A flexible region between residues 499 and 538 is not seen in the crystal structure but contains Ser-505, the approximate position of which is indicated by the arrow. The N-and C-termini of the protein are indicated. Adapted from A. Dessen (1999) and Ref. [24]. (See color plate section, plate no. 9.)...

Plate 10. Crystal structure of phos-phatidylinositol-PLC5 showing the C2 and catalytic domains. The position of the PH domain that would be attached to the EF-hand domain is indicated. The membrane surface would be parallel to the top surface of the molecule as shown. Calcium ions are shown bound to the active site and to the C2 domain. The position of inositol trisphosphate in space-filling format at the active site is indicated. Adapted from L.-O. Essen (1996) and Ref. [32]. (See page 325 in this volume.)... 

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