C-type lectin receptors

Extracellular or cell surface membrane receptors for D-galactose are widespread among higher eukaryotes. Isothermal titration calorimetry of the C-type lectin receptors from the tunicate Polyandrocatpa misakiensis revealed the presence of a single calcium atom per monomer with a dissociation constant of 2.6 pM, and confirmed the monosaccharide speci-... 

C-type lectin receptors (CLRs) are a family of proteins containing one or more structurally-related C-type, lectin-like domains. Transmembrane CLRs which mediate fungal binding include the mannose receptor (MR), Dectin 1, Dectin 2 and the dendritic cell receptor, DC-SIGN (reviewed in). ... 

Willment JA, Brown GD, Willment JA et al. C-type lectin receptors in antifungal immunity. Trends Microbiol 2008 16 27-32. 

GEUTENBEEK TB, GRiNGHUis SI (2009), Signalling through C-type lectin receptors shaping immune responses , Nat Rev Immunol, 9,465-79. 

C-type lectins Characterized by a Ca +-dependent carbohydrate recognition domain (CRD) includes the mammalian asialoglycoprotein receptor, the selectins, and the mannosebinding protein... 

Boyington, J. C., Riaz, A. N., Patamawenu, A., Coligan, J. E., Brooks, A. G., and Sun, P. D. (1999). Structure of CD94 reveals a novel C-type lectin fold Implications for the NK cell-associated CD94/NKG2 receptors. Immunity 10(1), 75-82. 

Drickamer, K. (1999). C-type lectin-like domains. Curr. Opin. Struct. Biol. 9(5), 585—590. Farag, S. S., Fehniger, T. A., Ruggeri, L., Velardi, A., and Caligiuri, M. A. (2002). Natural killer cell receptors New biology and insights into the graft-versus-leuke-mia effect. Blood 100(6), 1935-1947. 

Llera, A. S., Viedma, F., Sanchez-Madrid, F., and Tormo, J. (2001). Crystal structure of the C-type lectin-like domain from the human hematopoietic cell receptor CD69. /. Biol. Chem. 276(10), 7312-7319. 

The mannose receptor subfamily is a group of membrane-attached C-type lectins with multiple CRDs. Since most of these domains maintain neither calcium-binding nor sugarbinding properties, the term C-type lectin-like domain (CTLD) is more frequently used lately instead of the term CRD. The mannose receptor subfamily comprises four members including the mannose receptor, the M-type phospholipase A2... 

Coombs PJ, Graham SA, Drickamer K, Taylor ME. Selective binding of the scavenger receptor C-type lectin to Lewis... 

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