C. elegans

The cytosolic dyneins bear many similarities to axonemal dynein. The protein isolated from C. elegans includes a heavy chain with a molecular mass of approximately 400 kD, as well as smaller peptides with molecular mass ranging from 53 kD to 74 kD. The protein possesses a microtubule-activated ATPase... 

Selleck SB Genetic dissection of proteoglycan function in Drosophila and C. elegans. Semin Cell DevBiol 2001 12 127. 

The metabolism of pyrene and benzo[a]pyrene by C. elegans is increasingly complex. Pyrene is transformed by hydroxylation at the 1-, T and 6-, and 1- and 8- positions, and the bisphenols were glucosylated at the 6- and 8-positions the 1,6- and 1,8-pyrenequinones were also formed (Cerniglia et al. 1986). The same organism transformed benzo[fl]pyrene to the trany-7,8- and trans-... 

In both worm and fly, the Ras protein acts as a switch that determine cell fate. In C. elegans, the activation of Ras determines the formation of vulval as opposed to hypodermal (skin) cells (for sequence of events, see Table 8.4). In Drosophila photoreceptors, the activation of Ras determines the development of R7 as a neuronal as opposed to a cone cell. In both cases, Ras proteins operate downstream of receptor tyrosine kinases that are activated by cell-cell interactions. 

Nasmyth Some Rsk researcher must have knocked it out in C. elegans. 

Cell polarity and anaphase spindle positioning in the wild-type one-cell stage C. elegans embryo... 

Guo S, Kemphues KJ 1995 par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed. Cell 81 611— 620... 

Strome S, Wood WB 1983 Generation of asymmetry and segregation of germ-line granules in early C. elegans embryos. Cell 35 15—25... 

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