C CF3 groups

Further possibilities are opened up for investigation of fluoropolymers by two-dimensional methods. Thus, solid-state F COSY can be used to study potential spin exchange (see Ref. 17 for a nonpolymeric example), which may arise from chemical exchange (rare in polymeric systems, but conceivable for internal rotation of C—CF3 groups in asymmetric environments) or from spin diffusion. 

A number of research groups have investigated the Cu-mediated conversion of C-B bonds in to C-CF3 groups. Clearly this has been driven by the ready availability of boronate starting materials. In 2010, Qing combined copper triflate with the Ruppert-Prakash reagent, KF and silver carbonate to effect the desired transformation. The conditions described display a broad scope of functional group tolerance (Scheme 15.97). 

---