2- Butyl-4,4,6-trimethyl-1,3-dioxane

Butyl-4,4,6-trimethyl-1,3-dioxane. See Valeraldehyde hexyleneqlycol acetal... 

A patent (726) has described the preparation of 2methyl-pyrazine by reaction with ammonia and air at 350° over a catalyst containing vanadium pentoxide and potassium sulfate a series of cyanomethylpyrazines has been prepared from the corresponding methylpyrazines by reaction with sodium amide in liquid ammonia followed by Af-methyl-A -phenylcyanamide in dioxane (644). 2-Hydroxyiminomethylpyrazine has been prepared from 2-methylpyrazine, sodium amide, and liquid ammonia with butyl nitrite (727, 728), and 2-hydroxy-iminomethyl-3,6-dimethyI-5-pentylpyrazine similarly from 2,3,5-trimethyl-6-pentylpyrazine (648). Nitrones (28) have been prepared from 23-and 2,5-dimethyl-and tetramethylpyrazine through the substituted methylpyridinium (perchlorates) (27) by reaction with p-nitroso-A, fV-dimethylaniline (729). Dehydrogenation of ethylpyrazine at 600° over a calcium cobaltous phosphate catalyst gives 2-vinyl-pyrazine (658). 

Besides methanol, many other polar and nonpolar modifiers have also been used to successfully improve the separation in SFC. These modifiers include acetone, acetonitrile, acetic acid, butane, butanol, n-butyl chloride, carbon tetrachloride, dioxane, ethanol, formic acid, heptane, hexane, n-hexylamine, methylene chloride, nitromethane, propanol, proprionitrile, tetrahy-drofuran, toluene, triethanolamine, trifluoroacetic acid, trifluoroethanol, trimethyl phosphate, and water. 

Butyl-4,4,6-lrimethyl-1,3-dioxane 1,3-Dioxane, 2-butyl-4,4,6-trimethyl- EINECS 259-210-8. A flavorant. Quest UK. 

A report has appeared of the H n.m.r. spectra of some 4-methyl-6-alkyl-and 4,5,5-trimethyl-6-alkyl-l, 3-dioxans with and without methylation at C-2. The authors suggested that 2,2-r-4-trimethyl-/-6-t-butyl-l,3-dioxan (12) is in a twist conformation. 

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