Butanal, 4-phenyl

Poly[2,2-butane (4-phenyl)carbonate] 495 Poly[2,2-pentane Z (4-phenyl)carbonate] 493 ... 

Butan-3-one, 2-hydroxy-2-(indolyl)-photodecomposition, 4, 233 Butan-3-one, 2-hydroxy-2-(pyrrolyl)-photodecomposition, 4, 233 Butazolidines applications, 5, 782 Butazone, y-hydroxyphenyl-antiinflammatory agents, 5, 296 Butazone, phenyl-metabolism, 1, 239, 5, 301 synthesis, 5, 230 But-l-ene, 1-morpholino-polymers, 1, 291... 

Some polyketones have been used to synthesize diisoxazolyl alkanes, e.g., 1,4-di- (5 -phenyl-3 -isoxazoly 1) butane. ... 

A mixture of 7.3 parts l-chloro-4,4-di-(4-fluorophenyl)-butane, 5.1 parts l-phenyl-4-oxo-l,3,8-triaza-spiro(4,5)-decane, 4 parts sodium carbonate, a few crystals of potassium iodide in 200 parts 4-methyl-2-pentanone is stirred and refluxed for 60 hours. After cooling the reaction mixture is treated with water. The organic layer is separated, dried, filtered and evaporated. The solid residue is recrystallized from 80 parts 4-methyl-2-pentanone, yielding l-phenyl-4-oxo-8-[4,4-di-(4-fluorophenyl)-] butyl-1,3,8-triaza-spiro(4,5)decane, melting point 187.5° to 190°C. 

Finke, P. E., Oates, B., Mills, S. G., MacCoss, M., Malkowitz, L., Springer, M. S., Gould, S. L., DeMartino, J. A., Carella, A. Carver, G., et al. (2001). Antagonists of the human CCR5 receptor as anti-HIV-1 agents. Part 4 synthesis and structure—Activity relationships for l-[7V-(Methyl)-7V-(phenylsulfonyl)amino]-2-(phenyl)-4-(4-(7V-(alkyl)-7V-(benzylox-ycarbonyl)amino)piperidin-l-yl)butanes. Bioorg. Med. Chem. Lett. 11 2475-2479. 

Butyromtnle, 2-benzyl-2-phenyl- [Butane-nitrile, 2-benzyl-2-phenyl-], 55, 94 Butyromtnle, 4-bromo-2,2-diphenyl- [Bu-tanemtnle, 4-bromo-2,2-diphenyl-],... 

Butyromtnle, 3-methyl-2-phenyl- [Butane-mtnle, 3-methyl-2-phenyl-], 55, 102 Butyromtnle, 3-methyl-2-phenyl-2-vinyl-[Butanemtnle, 2-ethenyl-3-methyl-2-phenyl], 55, 102... 

Auch komplexe Kupfer(I)-hydride reduzieren hauptsachlich unter 1,4-Addition (Bil-dung gesattigter Aldehyde und Ketone)10. Einfacher ist die Reduktion mit Natrium- bzw. Kalium-tetracarbonyl-hydrido-ferrat einfacher En-one in waBrigem Methanol z.B. 3-Oxo-l-phenyl-butan (90% d.Th.) aus 3-Oxo-l-phenyl-buten11 bzw. von 2-Alkyliden-l,3-dionen in Athanol12 ... 

Gelegentlich wird auch Lithiumboranat als Reduktionsmittel eingesetzt. 4-Oxo-4-phe-nyl-butansaure liefert z.B. in Tetrahydrofuran 4-Phenyl-butan-4-olid (78% d.Th.)9. 

Mit Triathylsilan in Trifluoressigsaure erhalt man zumeist Carbonsauren, in gewissen Fallen die entsprechenden Lactone (s.a.S. 279f.). So wird z.B. aus 4-Oxo-4-phenyl-bu-tansaure in 73%iger Ausbeute 4-Phenyl-butan-4-olid erhalten4 ... 

Nitro-phenyl)-butanol-(2) — 2-(4-Nitro-phenyl)-butan 100%d.Th. 

Aus Stilben wird mit tert.-Butylchlorid bei -2,3 V ein 3 2-Gemisch aus 3,3-Dimethyl-1,2-diphenyl-butan und 2-Phenyl-1-(4-tert.-butyl-phenyl)-dthan5 erhalten. 

Beim BenzoyI-cyclopropan(- 1,38 V) erhalt man dagegen neben 1-Oxo-l-phenyl-butan iiberwiegend infolge Dimerisierung 1,2-Dicyclopropyl- , 2-diphenyl-glykolb. 

S)-tert-butoxy-corbonylomino-1,2(S)-epoxy-4-phenyl-butane (I)... 

ABSTRACT Zeolite Y modified with chiral sulfoxides has been foimd catal rtically to dehydrate racemic butan-2-ol enantioselectively depending on the chiral modifier used. Zeolite Y modified with R-l,3-dithiane-1-oxide shows a higher selectivity towards conversion of S-butan-2-ol and the zeolite modified with S-2-phenyl-3-dithiane-1-oxide reacts preferentially with R-butan-2-ol. Zeolite Y modified with dithiane oxide demonstrates a significantly higher catalsdic activity when compared to the unmodified zeolite. Computational simulations are described and a model for the catalytic site is discussed. 

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