Bursera microphylla

This is the smallest group of lignan tetrahydrofurans with fewer than ten members. All of reasonably well defined constitution are 3,4-trarw-disubstituted. Of these, most attention has been directed towards burseran, a constituent of Bursera microphylla with tumour-inhibiting properties (82). Optically pure (-)-/ra/w-burseran (82) and (-f-)-cw-burseran (83) were stereoselectively synthesized from chiral butyrolactones and gas chromatographic comparison indicated that the natural... 

Gum infections elephant tree (Bursera microphylla) or myrrh Comiphora spp ), oak bark or rhatany Krameria spp.) tinctures in combination. 

Investigation of Bursera microphylla has shown that the lignan burseran (LVII) is responsible for the cytotoxicity of the plant [247, 248]. The compound has an ED50 of 2-6 x 10 Hg/ml against KB cells in tissue culture. However, no experimental data are available on its in vivo activity against experimental neoplasms. 

---