Broussoaurone antioxidant activity

Broussoaurone A (48) Antioxidant activity (inhibition of lipid peroxidation) Inhibition of cyclooxygenase Platelet aggregation inhibitory activity11 [45] [43] [43] ... 

In an effort to investigate antioxidant constituents with antiproliferative effects in rat vascular smooth muscle cells (VSMC), broussoflavan A (36) [49], broussoflavonols F (45) [50] and G (46) [51], and broussoaurone A (48) [49] were found to inhibit the Fe2+-induced thiobarbituric acid-reactive substance formation in rat brain homogenate. Furthermore, broussoflavonols F (45) and G (46) inhibited fetal calf serum-, 5-hydroxytryptamine-, or ADP-induced [3H]thymidine incorporation into rat VSMC [45]. Antioxidant activities and inhibitory effects on proliferation of rat VSMC with potent antiplatelet activities of 45 and 46 may be useful for vascular diseases and atherosclerosis [43,45]. 

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See also in sourсe #XX -- [ , ]

See also in sourсe #XX -- [ , , ]

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