Bronchiolitis pulmonary function impairment

Effects Exposure to 0.01-0.1 ppm may cause irritation and dryness of the mucous membranes. Pulmonary function may be impaired at higher concentrations. Chronic exposure leads to bronchitis, bronchiolitis, pulmonary fibrosis, and emphysema. 

The commonest form of lung damage is an interstitial alveolitis, although pneumonitis and bronchiolitis obhter-ans have also been reported, as have sohtary localized fibrotic lesions, non-cardiac pulmonary edema, pleural effusions, acute respiratory failure, acute pleuritic chest pain, and adult respiratory distress syndrome (SEDA-17, 220) (SEDA-18, 201) (66-68). Amiodarone has also been reported to cause impairment of lung function, even in patients who do not develop pneumonitis (69), and preexisting impairment of lung function may constitute a contraindication to amiodarone. 

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