4-bromo-5-hydroxymethyl

Chromanone, 3-acetamido-2-methyl-reduction, 3, 729 Chromanone, 3-amino-synthesis, 3, 734 Chromanone, 3-arylidene-thermoisomerization, 3, 722 Chromanone, 3-benzylidene-thermolysis, 3, 728 Chromanone, 3-bromo-2-hydroxy-benzofuran from, 3, 729 Chromanone, 6,8-dimethyl-hydroxymethylation, 3, 731 Chromanone, 2,3-epoxy-as synthon, 3, 735... 

El-3-r/ ethyl-1,3-pentadiene (E)-1 -Bromo-2-isopropyl-1,3-butadiene (Z)-2-Hydroxymethyl-2-butenoic acid... 

Malonic acid, amino-, diethyl ester, HYDROCHLORIDE, 40, 24 Malonic acid, bts(hydroxymethyl)-, DIETHYL ETHER, 40, 27 Malonitrile, condensation with tetra-cyanoethylene, 41, 99 2-Mercaptopyrimidine, 43, 6S hydrochloride of, 43, 68 Mercuric oxide in preparation of bromo-cyclopropane, 43, 9 Mesityl isocyanide, 41,103 5-Methallyl-l,2,3,4,5-pentachlorocyclo-pentadiene, 43, 92 Methane, dimesityl-, 43, 57 Methanesiileinyl chloride, 40, 62 Methanesulfonic acid, solvent for making peroxybenzoic acid from benzoic acid, 43, 93... 

A novel route to 2-fhioromethyl- and 2-hydroxymethyl-4-alkylfurans was reported. Treating a-alkylacroleins with 1-bromo-l-trimethylsilylethylene in the presence of butyllithium yields 33. Oxidation of both double bonds followed by reaction with MsCl provides the key intermediate 34 vkdiich on treatment with TBAF produces the desired conqioimds <96TL7437>. 

Allylamino-6,7-dimethyl-2-quinoxalinecarboxylic acid Ar-Allyl-7-bromo-3-hydroxymethyl-2-quinoxalinecarboxamide 1,4-dioxide 3-(Allylcarbamoyl)methyl-l-methyl-2(177)-quinoxalinethione... 

Unsymmetric compartmental ligands that allow for the controlled synthesis of unsymmetric Ni2 or heterobimetallic NiM complexes have received particular attention.1876,1892 A wide range of such ligands derived particularly from 2-hydroxy-3-hydroxymethyl-5-methylbenzaldehyde and 2-hydroxy-3-hydroxymethyl-bromo-benzaldehyde has now been prepared and used for Ni com-plexation. These ligands have monopodal iminic pendent arms and either mono- or dipodal aminic pendent arms and the terminal donors of the pendent arms can be provided by pyridine, imidazole, and tertiary amino groups.1893-1897 Complexes are usually prepared by reaction of the requisite Ni11 salts with the preformed ligand. 

Double hydrophilic star-block (PEO-fo-PAA)3 copolymers were prepared by a combination of anionic and ATRP of EO and fBuA [150]. Three-arm PEO stars, with terminal - OH groups were prepared by anionic polymerization, using l,l,l-tris(hydroxymethyl)ethane, activated with DPMK as a trifunctional initiator. The hydroxyl functions were subsequently transformed to three bromo-ester groups, which were utilized to initiate the polymerization of f-butyl acrylate by ATRP in the presence of CuBr/PMDETA. Subsequent hydrolysis of the f-butyl groups yielded the desired products (Scheme 74). 

The formyl group in orthoformylselenophenecarboxylic acids on reduction to an hydroxymethyl group undergoes ring closure to lactones.100 To obtain 2,4-disubstituted selenophenes, 4-bromo-2-formylselenophene was prepared by the swamping catalyst method.101 Selenopheno[2,3-b]thiophene derivatives may be prepared from compound 84.102 Another route to substituted... 

Mit Di- -bromo-bis-[l,3- 3-3-methyl-2-butenyl)-nickel] erhalt man in Dimethylformamid bei 60° aus 2-Iod-imidazol (72%) bzw. 2-Brom-imidazol (68%) 2-(3-Methyl-2-buten-yl)-imidazol und aus 4(5)-Hydroxymethyl-2-iod-imidazol 4(5)-Hydroxymethyl-2-(3-methyl-2-buten-yl)-imidazol (45 %)943. 

Bis(bromomethyl)propane-l,3-diol is currently available with a purity of 98.5% (Ameribrom, 1996 Dead Sea Bromine Group, 1998). 2,2- Bis(bromomethyl)-propane-l,3-diol was available earlier as a technical product with a purity of 79%. Several impurities were identified in the technical product 2,2-bis(hydroxymethyl)-l-bromo-3-hydrox ropane, 2,2-bis(bromomethyl)-l-bromo-3-hydroxypropane and pentaerythritol (National Toxicology Program, 1996). 

---