Bromo glyoxylates from

As can be seen from Table 1 the method is general for a wide variety of activated halides, and provides an excellent alternative to selenium dioxide for the synthesis of 1,2-diketones and keto aldehydes. It constitutes, perhaps, the definitive synthesis of glyoxylates. It is not necessary to heat many a-bromo ketones since Ae reaction often proceeds smoothly at room temperature. 

Aldol reactions. Aldol products are obtained in good yields from reaction of ketones with glyoxylic acid monohydrate with assistance of ultrasound irradiation. Substrate-control (by 1,3- + 1,5-asynmietric induction) of the aldol reaction involving y-amino-a-ketoesters under solvent-free conditions is very effective.- With lithium dicyclohexylamide and InCl, the reaction of esters with aldehydes furnishes P-hydroxy esters, and that of a-bromo esters affords a,p-epoxy esters." These are typical Reformatsky and Darzens reaction products, respectively. 

---