Bromo-etherification process

In a bromo-etherification process, amino alcohols 147, derived from the chiral pool, cyclized in a 1-endo manner to give rise to a range of chiral polysubstituted 1,4-oxazepanes 148 in good yields with moderate-to-excellent regio- and diastereoselectivities. The regioselectivity observed was... 

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See also in sourсe #XX -- [ , ]

See also in sourсe #XX -- [ , ]

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