5-Bromo-deoxy-uridine

Br]-2 -Bromo-2-deoxy-uridine has been prepared either from 2,2 -anhydro-uridine using radio labelled ammonium bromide or by irradiation of unlabelled... 

In contrast to uridine,389 cytidine does not yield a 5 -chloro-5 -deoxy derivative on reaction with N,N-dimethyl(chlorometh-animinium) chloride instead 2,2 -anhydrocytidine is formed.395 However, thionyl chloride or bromide in hexamethylphosphor-amide at room temperature achieves this selective replacement of the primary hydroxyl group of halogen in cytidine, and also in adenosine, in respective yields of 80 and 75% for the chloro compounds, and 55 and 30% for the bromo analogs.396... 

Bromoethenyl) -2 -deoxyuridine, 9CI. 2 -Deoxy-5-(2-bromovinyl)uridine. Bromo-vinyl deoxyuridine. BVDU [82768 3]... 

Dibromo- and 2, 5 -dichloro-2, 5 -dideoxy derivatives of uridine and 5-substituted uridines have been obtained by treatment of the nucleosides with the appropriate Vilsmeier reagent a 2,2 -an-hydronucleoside intermediate was postulated to account for the observed retention of configuration at C-2. 5 -Bromo-5 -deoxy der-... 

Cyclouridine, 39B, 322 5-Bromo-2 -deoxyuridine, 31B, 183 1 i3-D-Arabinofuranosyl-5-bromouracil, 39B, 324 5-Bromouridine, 31B, 183 2 -Chloro-2 -deoxyuridine, 38B, 455 5-Chloro-2 -deoxyuridine, 39B, 324 5-Chlorouridine, 37B, 248 -Fluoro-2 -deoxy-/3-uridine, 29, 710 -Iodo-2 -deoxyuridine, 30B, 204 -lodouridine, 35B, 276... 

Later, this reaction was reexamined by using 5-bromo-2 -deoxy-3, 5 -bis-0-(trimethylsilyl)uridine ... 

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