Branched glycan

Y Kuroda, A Shibukawa, T Nakagawa. The role of branching glycan of human eq-acid glycoproten in enantioselective binding to basic drugs as studied by capillary electrophoresis. Anal Biochem 268 9-14, 1999. 

Dudkin et al. describe the synthesis of globally deprotected multi-branched glycans and these glycans are aminated prior to aspartylation with a hexapeptide, which is then extended using NCL to afford iV-linked glycopeptides for use as possible antigens against prostate... 

Branched glycans The branches are written within the parenthesis (). The designation of branch chain versns backbone chain follows ... 

Dextran, a branched glycan polymer, can be chemically sulfated to prepare dextran sulfate,21 having low anticoagulant activity.2 Dextran sulfate has been used as a heparin replacement in anticoagulation and has recently been immobilized on plastic tubes to prepare non-thrombogenic... 

Mannose H2, H3 5 Substitution within core region of branched glycan... 

Figure 2. Dependency of binding affinity on valency of branched -glycans. Curves marked Di, Tri, and Tetra refer to the results obtained with synthetic oligosaccharides PENTA-2,4, NONA I, and UNDECA in Figure 1.

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