Brain Inflammation and Neurogenesis

Previously, the brain was thought to be an immune-privileged organ. Now it is clear that the brain does respond to peripheral inflammatory stimuli through both neural and humoral afferent signals. The concept that the microglia act as the brain s immune system has also become widely accepted. The inflammatory responses in the brain have different features from those of nonneuronal tissues. Microglia activation and elevated levels of cytokines and 

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