Botulinum toxins chronic pain

The use of botulinum toxin has been increasing in cosmetic dermatology, muscle rigidity/spasticity syndromes, hyperhidrosis, some types of chronic pain syndromes, and headaches. It has the unfortunate distinction of being the most potent toxin that exists and is a weapon of mass destruction. 

Uses The uses of botulinum toxin in Parkinson s disease [54" ], anal fissure [55" ], women with chronic pain [56" ], spasticity after stroke in adults [57", 58 ], and urological conditions [59 have been reviewed. The pharmacology and formulations of botuhnum toxins and data from clinical trials, demonstrating their efficacy in dystonia, spasticity, tics, tremor, dysphonia, and autonomic disorders, have been reviewed [60 ]. 

Abbott J. Gynecological indications for the use of botulinum toxin in women with chronic pelvic pain. Toxicon 2009 54(5) 647-53. 

Uses The uses of botulinum toxin in Parkinson s disease [48"], anal fissure [49, and women with chronic pain [50 have been reviewed. 

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