Top-down vs. bottom-up approach

Shapiro, J. R, Bottom-up vs. Top-down Approaches to Supply Chain Management ami Modeling, Sloan School of Management, Massachusetts Institute of Technology, Cambridge, MA, 1998. 

FIGURE 1.7 (A) Bottom-up vs. (B) top-down approaches to proteomic analysis. Top-down... 

Explicitly model of the independencies vs. simulating the behavior of the Cl interconnected within the SoS and assess the strength of interdependencies as an emerging system property. The former is a top-down model which assumes the existence of interdependencies. The latter is bottom-up system description which maps the functional relations among components in different systems. ABM can be regarded as the bottom-up approach CN, SD, and DCST can represent system functionality as bottom-up approaches PN, BN and IIM require the identification of system dependencies and are top-down approaches. 

Fig. 3. Top-down vs. bottom-up MS proteomics-based approaches for microorganism identification.

---