Bone graft substitutes calcium phosphate cement

Key words putty, cement, bone graft substitute, calcium phosphate, injectable. 

Even though the first studies dealing with ceramic bone substitutes are more than 100 years old, it was only in the 1970s that research soared." In the early days, studies were focused mainly on porous blocks and granules." However, the discovery of calcium phosphate cements (CPC) in 1982-1983 opened up a new era in which the handling properties of bone graft substitute became of paramount importance. 

The compressive strength of calcium phosphate cement is 4—10 times greater than cancellous bone and has the highest mechanical strength of any osteo-conductive bone graft substitute [27, 47]. 

Horstmann, W.G., Verheyen, C.C.P.M., Leemans, R. 2003. An injectable calcium phosphate cement as a bone-graft substitute in the treatment of displaced lateral tibial plateau fractures. Injury 34(2), 141-144. 

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