Temperature bonding response

In many ways, hydrogen bonds are responsible for life on Earth. They cause water to be a liquid rather than a gas at ordinary temperatures, and they are the primary intermolecular force that holds huge biomolecules in the shapes needed to play their essential roles in biochemistry. Deoxyribonucleic acid (DNA), for instance, contains two long molecular strands coiled around each other and held together by hydrogen bonds. 

Hydrogen bonding is responsible for the strong, temperature-dependent self- and hetero-assoeiation of amphiprotie solvents e.g. water, aleohols, amides). 

Additionally, McCormick et al. utilized imine bonds for the preparation of reversible imine SCL micelles. They synthesized a temperature-responsive triblock copolymer, a-methoxypoly(elhylene oxide)- -poly(A-(3-aminopropyl) methacryIamide)-fc-poly((V-isopropyIaCTyIamide) (mPEO-PAPMA-PNIPAM), via aqneons RAFT polymerization. By inCTeasing the solution temperature above the LCST of the PNIPAM block, the polymers self-assembled into micelles. Subsequently, the PAPMA shell was cross-linked with terephthaldicarboxaldehyde to generate SCL micelles with cleavable imine linkages (Figure 54.16). 

---