Bombesin analogues

K. Fujimoto, R. Doi, R. Hosotani, M. Wada, J.-U. Lee, T. Koshiba, T. Ibuka, H. Habashita, K. Nakai, N. Fujii, M. Imamura, Effects of structural modulation on biological activity of bombesin analogues with ( )-alkene bond. Life Sci. 60 (1997) 29-34. 

LA BELLA, R., et al., In vitro and in vivo evaluation of a Tc(I)-labelled bombesin analogue for imaging of gastrin releasing peptide receptor-positve tumours, Nucl. Med. Biol. 29 (2002) 553-560. 

BREEMAN, W.A., et al.. Evaluation of radiolabelled bombesin analogues for receptor-targeted scintigraphy and radiotherapy, Int. J. Cancer 81 (1999) 658-665. 

A new high-affinity technetium-99m-bombesin analogue with low abdominal accumulation has been recently published (Lin et al. 2005). 

Lin KS, Luu A, Baidoo KE et al (2005) A new high affinity technetium-99m-bombesin analogue with low abdominal accumulation. Bioconjug Chem 16 43-50 Liu G, Mangera K, Liu N et al (2002) Tumor pretargeting in mice using " Tc-labelled morpholino,... 

Nock B, Nikolopoulou A, Chiotellis E et al (2003) " Tc-Demobesin 1, a novel potent bombesin analogue for GRP receptor-targeted tumour imaging. Eur J Nucl Med Mol Imaging 30 247-258 Okarvi SM (2004) Peptide-based radiopharmaceuticals future tools for diagnostic imaging of cancers and other diseases. Med Res Rev 24 357-397... 

Fig. 6 A rhenium tricarbonyl complex conjugated to a bombesin analogue and an inter-calator, compound 7, visualised in fixed PC-3 cells by fluorescence microscopy (left), where green represents the complex and blue the DAPI nuclear stain.

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