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Blood vessels angiogenesis inhibiting compounds

Compound efficacy has been correlated with the inhibition of angiogenesis in a variety of assays (endothelial capillary tube formation, aortic ring assay, chorioallantoic membrane assay, real-time tumor blood flow and PO2 measurements, tumor blood vessel density, and tumor hypoxic and apoptotic fractions) [35]. [Pg.226]

Shi et al. reported on the synthesis and antiangiogenic activities of lino-mide and its analogs (compounds 11-16) [32], Three of the analogs are 3.3-69 times more potent than linomide at inhibiting blood vessel formation in the chicken chorioallantoic membrane (CAM) [41,42] angiogenesis assay. These compounds possessed considerable antiproliferative activities against isolated human umbilical vein endothelial (HUVEC) cells along with with no... [Pg.226]

See other pages where Blood vessels angiogenesis inhibiting compounds is mentioned: [Pg.826]    [Pg.717]    [Pg.678]    [Pg.18]    [Pg.367]    [Pg.600]    [Pg.75]    [Pg.61]    [Pg.155]    [Pg.73]    [Pg.11]    [Pg.23]    [Pg.4346]    [Pg.2204]    [Pg.189]   
See also in sourсe #XX -- [ Pg.5 , Pg.216 , Pg.217 , Pg.218 , Pg.219 ]



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Angiogenesis

Angiogenesis compounds inhibiting

Angiogenesis inhibition

Blood compounds

Blood vessel angiogenesis

Blood vessels

Compound vessels

Inhibition compounds

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