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Blood coagulation pathway effects

There is no doubt that phosphatidylserine is active in the above reactions. However, in neither of these two systems has the importance of this phosphoglyceride in an in vivo system been defined. Certainly in the protein kinase C studies, there appeared to be no real attempt to explore the effect of mixtures of phospholipids (which might be encountered in the cell) on the kinase activity. In the blood coagulation pathway, it is well established that phosphatidylserine-phosphatidylcholine mixtures with the proper net negative charge are key in the formation of the active prothrombinase. Consequently, there is a general assumption by many investigators in this field that phosphatidylserine is the key component. [Pg.163]

EFFECTS ON HUMAN BLOOD COAGULATION PATHWAY 19.3.1 Human Blood Coagulation Pathway... [Pg.257]

See other pages where Blood coagulation pathway effects is mentioned: [Pg.251]    [Pg.138]    [Pg.755]    [Pg.79]    [Pg.193]    [Pg.410]    [Pg.256]    [Pg.368]    [Pg.2549]    [Pg.141]    [Pg.837]    [Pg.140]    [Pg.894]    [Pg.607]    [Pg.10]    [Pg.30]    [Pg.61]    [Pg.59]    [Pg.10]    [Pg.4]    [Pg.59]    [Pg.951]    [Pg.183]    [Pg.527]    [Pg.580]    [Pg.3678]    [Pg.262]    [Pg.206]    [Pg.580]   
See also in sourсe #XX -- [ Pg.257 ]



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