12 bit CCD-camera

First, two-dimensional gels must be digitized. In most cases, this is achieved by the use of a laser densitometer, a CCD camera or a phosphor imager [32]. These pieces of equipment produce images of typically around 2000 x 2000 pixels or more, and a depth of 12 or 16 bits, thus providing a dynamic range of 4096, respectively 65 536 grey levels. 

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