Bisplatinum complexes

The use of aromatic dicarboxylates as leaving groups led to studies on tri-and tetra-carboxylates and some interesting bisplatinum complexes containing two Pt(am)2 groups bridged by the polycarboxylate [42, 43]. Thus, for a 1,2,4,5-tetracarboxylate a general structure is ... 

Yamago developed a conceptually different synthetic route and demonstrated the selective synthesis of [8]CPP, which was the smallest CPP prepared at that time (Scheme 6.2c) [16]. The synthesis utilized the cis coordination of bisaryl platinum complexes as a structural motif for making a cyclic structure, and platinum square 14 was prepared by transmetallation of 4,4 -bisstannylated biphenyl 13c (X = SnMe3) and Pt(cod)Cl2 (cod refers to 1,5-cyclooctadiene). Compound 14 was also prepared stepwise by transmetallation of 13c to bisplatinum 13d and subsequent reaction between 13c,d. Once 14 was formed, ligand exchange from cod to dppf [dppf refers to l,3-bis(diphenylphosphino)ferrocene] and subsequent reductive elimination of platinum by employing bromine afforded [8] CPP. 

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