Bis ethoxycarbonyl methylene

Hirsch, A., Lamparth, I., and Grdsscr, T. (1994) Regiochemistry of multiple additions to the fullerene core Synthesis of a T -symmetric hexakisadduct of Ca with bis(ethoxycarbonyl)methylene. J. Am. Chem. Soc. 116, 9385-9386. 

Unlike the reversed shift of the emission band compared to the dihydrogen addend type, the singlet lifetime in the bis- and tris(bis-(ethoxycarbonyl)-methylene) derivatives is increased comparable to the former multiple adducts. The values range from 1.7 to 3.1 ns (tris-adduct), depending on the distorted T7-electron system of the fullerene core [67,108], In comparison to C6o, the fluorescence quantum yield for the malonic ester hexaadduct is increased by the factor 10 (30 X 10 4) [67,111], In the case of both pyrrolidino hexa-adducts (Th 14 and D3 15, Fig. 13), the effect is remarkably higher. The fluorescence quantum yields are increased about 100-fold (-0.02) compared to C6o. On the other hand, the singlet lifetime is only partly increased with -3.5 ns [111,112],... 

The 6-bis(ethoxycarbonyl)methylene derivative of 9-ribosylpurine 195 obtained by condensation of 6-thioinosine 1-methiodide 194 with diethyl sodiomalonate underwent a Dimroth rearrangement to afford 3-) -D-ribofuranosyl-IbP 196 derivative on heating in methanolic potassium hydroxide (81H1049). 

Nitropyrimidinone 3 is also confirmed to be a suitable substrate for RTF reaction. When pyrimidinone 3 is allowed to react with diethyl 3-oxo-pentanedioate 19b in the presence of triethylamine, the RTF reaction effectively proceeds to afford 3,5-bis(ethoxycarbonyl)-4-pyridone 21b (Scheme 11). The C2 - N1 - C6 moiety of pyridone 21b is derived from 3, which means that nitropyrimidinone 3 behaves as the synthetic equivalent of activated di-formylamine 5. While 2,4,6-heptanetrione 19d causes the RTF reaction under the same conditions, giving 21d, ethyl 3-oxobutanoate requires conversion to sodium enolate 13a for preparation of 21a, due to the presence of only a single active methylene group [40]. 

Als Enol-ether von 1,3-Dicarbonyl-Verbindungen und 3-Oxo-alkansaure-estern reagieren 5-Aryl-2-(ethoxycarbonyl-methylen)-4-methyl-3-oxo-2,3-dihydro-furane mil 70%iger Hy-drazin-Hydrat-Losung zu 3(5),3 (5 )-Bi-lH-pyrazolylen988. 

Fordos, E., Ungvari, N., Kegl, T. and Ungvary, F. (2006) Reactions of with ethoxycarbonylcarbene-bridged dicobalt carbonyl complexes [p2- ethoxycarbonyl (methylene) -p2- (carbonyl) -bis (tricarbonyl-cobalt) (Co-Co)] and [di-p2- ethoxycarbonyl (methylene) -bis (tricarbonyl-cobalt) (Co-Co)]. European Journal of Inorganic Chemistry, 1875-1880. 

The behavior of bis(heteroaryl)methanes in which the heterocycle was an electron-withdrawing group was similar to that typically exhibited by active methylene compounds. Bis(2-benzothiazolyl)methane and bis(2-(5-ethoxycarbonyl-4-methyl)thiazolyl)methane readily underwent azo-coupling with benzenediazonium chloride, nitrosation with nitrous acid and condensation with aromatic aldehydes under mildly basis conditions, such as in the Knoevenagel procedure. [94G301]... 

Harnstoff l,3-Bis-[butyloxy-carbonyl]- E4, 1322 (ROOC-NH2 + COCl2) Isoharnstoff l-(Diethoxy-methylen)-3-ethoxycarbonyl-O-ethyl- E4, 1365 [COCl2 + (RO)2C = NH] Malonsaure [Amino-(2-hydroxy-ethylamino)-methylen]- -lert.-butylester-methylester E15/2, 2155 (CC13 - NH-R)... 

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